Molecular discovery
Investigating the barriers to lasting treatments.
Cure-directed research connecting beta-cell function, immune processes and molecular evidence to questions that can be independently tested.
Which biological connections stand up to independent scrutiny?
Our proposed approach
Preserve the differences between DNA, RNA, proteins and metabolites.
Connect findings to tissue, assay, population and source.
Investigate barriers to durable islet function, immune compatibility, safety and access through qualified collaborations.
What we aim to build.
A traceable molecular evidence resource and computational research tools. An association is a starting point for investigation, not proof of a treatment effect.
Research program · In developmentThe scientific foundation.
Hierarchical inference and multiple-testing control
Cell identity, tissue and disease context
Genetics, proteins, metabolites and assay chemistry
Independent donors, assays and functional evidence
The foundation behind the work
Data. Models. Scientific understanding.
We are building a shared diabetes evidence library, the Metra model research program and Foundry’s controlled data workflows to support our research and future applications.
Research partnerships
Help build better
diabetes research.
Discuss a study, a data source or a practical need with us.
Contact us